Normofractionated stereotactic radiotherapy versus CyberKnife-based hypofractionation in skull base meningioma: a German and Italian pooled cohort analysis.
Conti AlfredoSenger CarolinAcker GülizKluge AnnePontoriero AntonioCacciola AlbertoPergolizzi StefanoGermanò AntoninoBadakhshi HarunKufeld MarkusMeinert FranziskaNguyen PhuongLoebel FranziskaVajkoczy PeterBudach VolkerDavid KaulPublished in: Radiation oncology (London, England) (2019)
This analysis of pooled data from three centers showed excellent LC and low side effect rates for patients treated with CK-hFSRT or nFSRT. The efficacy, safety, and convenience of a shortened treatment period provide a compelling case for the use of CK-hFSRT in patients with moderate size skull base meningioma and provided that OAR constraints are met.
Keyphrases
- protein kinase
- early stage
- optic nerve
- radiation therapy
- electronic health record
- tyrosine kinase
- high intensity
- big data
- phase iii
- radiation induced
- simultaneous determination
- randomized controlled trial
- locally advanced
- mass spectrometry
- machine learning
- data analysis
- study protocol
- high resolution
- optical coherence tomography