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Nanoencapsulation of Eggplant ( Solanum melongena L.) Peel Extract in Electrospun Gelatin Nanofiber: Preparation, Characterization, and In Vitro Release.

Danya Elizabeth Estrella-OsunaJosé Agustín Tapia-HernándezSaúl Ruíz-CruzEnrique Márquez-RíosJosé de Jesús Ornelas-PazCarmen Lizette Del-Toro-SánchezVíctor Manuel Ocaño-HigueraFrancisco Rodríguez-FélixMaría Isabel Estrada-AlvaradoLuis Alberto Cira-Chávez
Published in: Nanomaterials (Basel, Switzerland) (2022)
This study describes the preparation and characterization of eggplant peel extract-loaded electrospun gelatin nanofiber and study of its in vitro release. Results obtained by scanning electron microscopy (SEM) and transmission electronic microscopy (TEM) micrograph revealed that eggplant peel extract-loaded electrospun gelatin nanofiber is in nanometric range with an average diameter 606.7 ± 184.5 and 643.6 ± 186.7 nm for 20 and 33.3 mg mL -1 of extract addition, respectively. Moreover, the incorporation of extract improved morphology by being smooth, homogeneous, and without account formation compared to nanofibers without extract (control). Fourier transform-infrared (FT-IR) spectra indicated that interaction exists between electrospun gelatin nanofiber and eggplant peel extract by hydrogen bond interactions, mainly. Electrospun gelatin nanofibers showed encapsulation efficiency greater than 90% of extract and a maximum release of 95 and 80% for the medium at pH 1.5 and 7.5, respectively. Therefore, the electrospinning technique is a good alternative for the conservation of bioactive compounds present in the eggplant peel through electrospun gelatin nanofiber.
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