Depletion and enrichment of phytosterols in soybean oil lipid emulsions directly associate with serum markers of cholestasis in preterm parenteral nutrition-fed pigs.

Greg GuthrieBarbara StollShaji ChackoMahmoud MohammadCandace StyleMariatu VerlaOluyinka O OlutoyeDeborah SchadyCharlotte LauridsenNick TatarynDouglas G Burrin

Published in: JPEN. Journal of parenteral and enteral nutrition (2021)

The increase in serum direct bilirubin was lower in the DEP group vs the lipid emulsions with normal or ENR phytosterols. Our results provide additional evidence that phytosterols are linked to an increase in serum markers of cholestasis in preterm PN-fed pigs.

Keyphrases

fatty acid
preterm birth
low birth weight
gestational age
drug induced