Systemic inflammatory response in robot-assisted and laparoscopic surgery for colon cancer (SIRIRALS): study protocol of a randomized controlled trial.
Pedja CukAndreas Kristian PedersenKate Lykke LambertsenChristian Backer MogensenMichael Festersen NielsenPer HelligsøIsmail GögenurMark Bremholm EllebækPublished in: BMC surgery (2021)
To our knowledge, this is the first clinical randomized controlled trial to clarify the inflammatory stress response induced by robot-assisted or laparoscopic surgery for colon cancer resections. Trial registration This trial is registered at Clinicaltrials.gov (Identifier: NCT04687384) on December, 29, 2020, Regional committee on health research ethics, Region of Southern Denmark (N75709) and Data Protection Agency, Hospital Sønderjylland, University Hospital of Southern Denmark (N20/46179).
Keyphrases
- robot assisted
- laparoscopic surgery
- study protocol
- randomized controlled trial
- inflammatory response
- minimally invasive
- clinical trial
- healthcare
- big data
- open label
- phase iii
- phase ii
- public health
- electronic health record
- placebo controlled
- lipopolysaccharide induced
- emergency department
- machine learning
- double blind
- lps induced
- adverse drug
- immune response
- systematic review
- acute care
- liver metastases
- drug administration
- deep learning