Human umbilical cord mesenchymal stem cells ameliorate colon inflammation via modulation of gut microbiota-SCFAs-immune axis.

Airu LiuXiaonan LiangWenxin WangChen WangJia SongJinbo GuoDonglei SunDong WangMei SongJiaming QianXiao-Lan Zhang

Published in: Stem cell research & therapy (2023)

The present study advances understanding of MSCs in the protective effects on colitis, providing evidence for the new role of the microbiome-metabolite-immune axis in the recovery of colitis by MSCs.

Keyphrases

umbilical cord
mesenchymal stem cells
bone marrow
endothelial cells
oxidative stress
cell therapy
ulcerative colitis
pluripotent stem cells