Patterns of pharmacotherapy for bipolar disorder: A GBC survey.
Balwinder SinghAnastasia K YocumRebecca StrawbridgeKatherine E BurdickCaitlin E MillettAmy T PetersSarah H SperryGiovanna FicoEduard VietaNorma VerdoliniOphelia GodinMarion LeboyerBruno EtainIvy F TsoBrandon J CoombesMelvin G McInnisAndrew A NierenbergAllan H YoungMelanie M AshtonMichael BerkLana J WilliamsKamyar KeramatianLakshmi N YathamBronwyn J OversJanice M FullertonGloria RobertsPhilip B MitchellOle A AndreassenAna Cristina AndreazzaPeter P ZandiDaniel PhamJoanna M BiernackaMark A Fryenull nullPublished in: Bipolar disorders (2023)
Mood-stabilizing anticonvulsants, second-generation antipsychotics, and antidepressants were the most prescribed medications suggesting prescription patterns that are not necessarily guideline concordant. Significant differences exist in the prescription practices across different geographic regions, especially the underutilization of lithium in the North American cohorts and the higher utilization of first-generation antipsychotics in the European cohorts. There is a need to conduct future longitudinal studies to further explore these differences and their impact on outcomes, and to inform and implement evidence-based guidelines to help improve treatment practices in BD.