Validating a non-invasive, ALT-based non-alcoholic fatty liver phenotype in the million veteran program.

Marina Serper Marijana Vujkovic David E KaplanRotonya M CarrKyung Min LeeQing ShaoDonald R MillerPeter D ReavenLawrence S PhillipsChristopher J O'DonnellJames B MeigsPeter W F WilsonRachel Vickers SmithHenry R KranzlerAmy C JusticeJohn M GazianoSumitra MuralidharSaiju PyarajanScott L DuVallThemistocles L AssimesJennifer S LeePhilip S TsaoDaniel J RaderScott M DamrauerJulie A LynchDanish SaleheenBenjamin F VoightKyong-Mi Changnull null

Published in: PloS one (2020)

We validate a simple, non-invasive ALT-based NAFLD phenotype using EHR data by leveraging previously established NAFLD risk-associated genetic polymorphisms.

Keyphrases

electronic health record
quality improvement
big data
fatty acid
machine learning
artificial intelligence