Hypoxia-Preconditioned Bone Marrow Mesenchymal Stem Cells Improved Cerebral Collateral Circulation and Stroke Outcome in Mice.

Cungen Ma Xinxuan YangJiahui ZhaoXiran LiuXin LiuYuan CaiAlexandra WehbeYuchuan DingShanping YuLing WeiLi-Ping Liu

Published in: Arteriosclerosis, thrombosis, and vascular biology (2023)

BMSCs increased collateral circulation and improved poststroke outcomes, through the upregulation of Rabep2. These effects were enhanced by hypoxic preconditioning.

Keyphrases

cerebral ischemia
subarachnoid hemorrhage
atrial fibrillation
poor prognosis
cell proliferation
ischemia reperfusion injury
high fat diet induced
type diabetes
adipose tissue
insulin resistance
skeletal muscle
blood brain barrier
upper limb
long non coding rna