Stability and Change in Biopsychosocial Factors Associated With Fatigue 6 and 12 Months After Traumatic Brain Injury: An Exploratory Multilevel Study.

Daniel LøkeNada AndelicEirik HelsethOlav VassendStein AnderssonJennie L PonsfordCathrine TverdalCathrine BrunborgMarianne Løvstad

Published in: The Journal of head trauma rehabilitation (2022)

The study demonstrated that several previously implicated factors show robust effects in distinguishing individuals with TBI on levels of fatigue, but only a few show additional within-subject associations across time. Pain severity, somatic symptom burden, psychological distress, and behavioral inhibition correlated with fatigue across time, implicating these factors as crucial targets for rehabilitation of patients with TBI who suffer from persistent fatigue.

Keyphrases

sleep quality
traumatic brain injury
chronic pain
gene expression
depressive symptoms
risk factors
physical activity
spinal cord
mild traumatic brain injury
genome wide