Cross-sectional study of a United Kingdom cohort of neonatal vein of galen malformation.
Francesca LecceFergus RobertsonAdam RennieAnne-Marie HeuchanPaula ListerSanjay BhateJo BhattacharyaStefan BrewLakshmi KanagarajahAdam KuczynskiMark J PetersDeborah RidoutAnne SchmittClaire ToolisFaraneh Vargha-KhademVijeya GanesanPublished in: Annals of neurology (2018)
Despite modern supportive and endovascular treatment, more than one-third of unselected newborns with vein of Galen malformation did not survive. Outcome was good in around half of survivors. The importance of white matter injury suggests that abnormalities of venous as well as arterial circulation are important in the pathophysiology of brain injury. Ann Neurol 2018;84:547-555.