Traditional Chinese Medicine Shi-Bi-Man regulates lactic acid metabolism and drives hair follicle stem cell activation to promote hair regeneration.
Haojie DuTao ZhangQiao WangXinran CaoHuiwen ZhengJiabin LiJianxia ZhuJiao QuLehang GuoYang SunPublished in: Chinese medicine (2023)
SBM significantly promotes hair regeneration in cynomolgus monkeys. Mechanically, SBM can up-regulate LDHA-mediated lactic acid metabolism and drive HFSC activation, which in turn promotes the proliferation and differentiation of HFSCs.