The prognostic value of NRF2 in breast cancer patients: a systematic review with meta-analysis.

Micaela Almeida Mafalda Soares Ana Cristina Ramalhinho José Fonseca Moutinho Luiza Breitenfeld Luísa Pereira

Published in: Breast cancer research and treatment (2019)

These results suggest that tumours that overexpress NRF2 have a worse clinical outcome. Thus, NRF2 expression could be a marker for the prognostic of breast cancer patients and, in the future, it would be pertinent to focus on improving treatment efficacy for patients with NRF2 overexpression.

Keyphrases

oxidative stress
poor prognosis
transcription factor
current status
long non coding rna
combination therapy
replacement therapy
smoking cessation