Stability of Mosaic Divergent Repeat Interruptions in X-Linked Dystonia-Parkinsonism.

Joshua LaßTheresa LüthKathleen SchlüterSusen SchaakeBjörn-Hergen LaabsChristoph MuchRoland Dominic Go JamoraRaymond L RosalesGerard SaranzaCid Czarina E DiestaChristopher E PearsonInke R KönigNorbert BrüggemannChristine KleinAna WestenbergerJoanne Trinh

Published in: Movement disorders : official journal of the Movement Disorder Society (2024)

Our results show that a higher AGGG frequency may stabilize repeats across generations. This highlights the importance of further investigating mDRILS as a disease-modifying factor with generational differences. © 2024 The Authors. Movement Disorders published by Wiley Periodicals LLC on behalf of International Parkinson and Movement Disorder Society.

Keyphrases

early onset
parkinson disease
drug induced
randomized controlled trial
systematic review