Sex differences in brain atrophy in dementia with Lewy bodies.
Javier OltraAnnegret HabichChristopher G SchwarzZuzana NedelskaScott A PrzybelskiAnna InguanzoPatricia Diaz-GalvanVal J LoweKetil OppedalFrederic BlancAfina W LemstraJakub HortAlessandro PadovaniIrena RektorováLaura BonanniFederico MassaMilica G KrambergerJohn Paul TaylorJón G SnædalZuzana WalkerAngelo AntoniniBàrbara SeguraCarme JunqueErik WestmanBradley F BoeveDag AarslandKejal KantarciDaniel FerreiraPublished in: Research square (2023)
This study demonstrates sex differences on brain atrophy in probable DLB. While male DLB patients have a more widespread pattern of cortical atrophy at younger ages, these sex differences tend to disappear with increasing age. Longitudinal studies will help establish these cross-sectional findings and inform on sex and age considerations to the use of MRI in clinical routine, as the field moves towards precision medicine.
Keyphrases
- cross sectional
- end stage renal disease
- ejection fraction
- white matter
- newly diagnosed
- resting state
- chronic kidney disease
- magnetic resonance imaging
- peritoneal dialysis
- mild cognitive impairment
- prognostic factors
- clinical practice
- parkinson disease
- magnetic resonance
- diffusion weighted imaging
- subarachnoid hemorrhage