Effects of non-invasive ventilation on sleep in chronic hypercapnic respiratory failure.
Neeraj M ShahJoerg SteierNicholas HartNeeraj Mukesh ShahPublished in: Thorax (2023)
Chronic respiratory disease can exacerbate the normal physiological changes in ventilation observed in healthy individuals during sleep, leading to sleep-disordered breathing, nocturnal hypoventilation, sleep disruption and chronic respiratory failure. Therefore, patients with obesity, slowly and rapidly progressive neuromuscular disease and chronic obstructive airways disease report poor sleep quality. Non-invasive ventilation (NIV) is a complex intervention used to treat sleep-disordered breathing and nocturnal hypoventilation with overnight physiological studies demonstrating improvement in sleep-disordered breathing and nocturnal hypoventilation, and clinical trials demonstrating improved outcomes for patients. However, the impact on subjective and objective sleep quality is dependent on the tools used to measure sleep quality and the patient population. As home NIV becomes more commonly used, there is a need to conduct studies focused on sleep quality, and the relationship between sleep quality and health-related quality of life, in all patient groups, in order to allow the clinician to provide clear patient-centred information.
Keyphrases
- sleep quality
- respiratory failure
- extracorporeal membrane oxygenation
- depressive symptoms
- mechanical ventilation
- physical activity
- clinical trial
- case report
- acute respiratory distress syndrome
- randomized controlled trial
- metabolic syndrome
- positive airway pressure
- healthcare
- intensive care unit
- end stage renal disease
- obstructive sleep apnea
- cystic fibrosis
- drug induced
- insulin resistance
- adipose tissue
- skeletal muscle
- prognostic factors
- weight gain
- health information