Efficacy and Safety of Weekly Somatrogon vs Daily Somatropin in Children With Growth Hormone Deficiency: A Phase 3 Study.

Cheri L DealJoel SteelmanElpis VlachopapadopoulouRenata StawerskaLawrence A SilvermanMoshe PhillipHo-Seong KimCheolWoo KoOleg MalievskiyJose F CaraCarl L RolandCarrie Turich TaylorSrinivas Rao ValluriMichael P WajnrajchAleksandra PastrakBradley S Miller

Published in: The Journal of clinical endocrinology and metabolism (2022)

The efficacy of once-weekly somatrogon was noninferior to once-daily somatropin, with similar safety and tolerability profiles. (ClinicalTrials.gov no. NCT02968004).

Keyphrases

growth hormone
open label
physical activity
placebo controlled
double blind
clinical trial
randomized controlled trial