Intravenous acetaminophen does not reduce morphine use for pain relief in emergency department patients: A multicenter, randomized, double-blind, placebo-controlled trial.
Bruno MinottiGregory MansellaRobert SieberAlexander OttChristian H NickelRoland BingisserPublished in: Academic emergency medicine : official journal of the Society for Academic Emergency Medicine (2022)
In ED patients, acetaminophen had no additional effect on pain control or morphine-sparing effect at the time of first morphine administration. Titrated morphine with the algorithm used was highly effective, with 80% of all patients reporting pain relief within 60 min of starting therapy.
Keyphrases
- emergency department
- double blind
- end stage renal disease
- newly diagnosed
- ejection fraction
- chronic kidney disease
- chronic pain
- clinical trial
- peritoneal dialysis
- prognostic factors
- placebo controlled
- neuropathic pain
- stem cells
- randomized controlled trial
- open label
- high dose
- low dose
- bone marrow
- deep learning
- patient reported
- phase ii
- study protocol
- smoking cessation
- postoperative pain