Attrition when providing antiretroviral treatment at CD4 counts >500cells/μL at three government clinics included in the HPTN 071 (PopART) trial in South Africa.
Peter BockGeoffrey FattiNathan FordKaren JenningsJames KrugerColette GunstFrançoise LouisNelis GrobbelaarKwame ShanaubeSian FloydAshraf GrimwoodRichard HayesHelen AylesSarah FidlerNulda Beyersnull nullPublished in: PloS one (2018)
Attrition in this study was high, particularly during the first six months of treatment. Attrition was highest amongst clients starting ART at baseline CD4 counts > 500 cells/μL. Strategies to improve retention amongst ART clients, particularly those starting ART at baseline CD4 counts >500cells/μL, need strengthening. Improved monitoring of clients moving in and out of ART care and between clinics will assist in better understanding attrition and ART coverage in high burden countries.
Keyphrases
- induced apoptosis
- hiv infected
- cell cycle arrest
- south africa
- antiretroviral therapy
- primary care
- healthcare
- endoplasmic reticulum stress
- hiv positive
- clinical trial
- palliative care
- peripheral blood
- cell death
- human immunodeficiency virus
- randomized controlled trial
- nk cells
- hepatitis c virus
- pi k akt
- affordable care act