A Controlled Biodegradable Triboelectric Nanogenerator Based on PEGDA/Laponite Hydrogels.
Zhe LiCong LiWei SunYuan BaiZhou LiYu-Lin DengPublished in: ACS applied materials & interfaces (2023)
Implantable and wearable transient electronics based on nanogenerators have been applied in self-powered sensing, electrical-stimulation therapy, and other fields. However, the existing devices have a poor ability to match with the shapes of human tissues, and the degradation processes cannot meet individual needs. In this work, a PEGDA/Lap nanocomposite hydrogel was prepared that was based on biocompatible polyglycol diacrylate (PEGDA) and laponite, and a biodegradable single-electrode triboelectric nanogenerator (BS-TENG) was built. The PEGDA/Lap hydrogel has enhanced flexibility and mechanical and electrical performance. Its strain was 1001.8%, and the resistance was 10.8. The composite hydrogel had a good biocompatibility and could effectively promote the adhesion of cells. The BS-TENG could be used as a self-powered device to light an LED and serve as an active sensor for real-time monitoring of breath and various human movements. More importantly, the device could be degraded controllably without any harm. Therefore, BS-TENGs will be mainstream in diagnosis and treatment and play an important role in biomedical science.
Keyphrases
- drug delivery
- endothelial cells
- tissue engineering
- hyaluronic acid
- drug release
- wound healing
- induced pluripotent stem cells
- induced apoptosis
- pluripotent stem cells
- gene expression
- spinal cord injury
- staphylococcus aureus
- stem cells
- cell cycle arrest
- heart rate
- mesenchymal stem cells
- oxidative stress
- cystic fibrosis
- high resolution
- gold nanoparticles
- blood pressure
- cell proliferation
- cell therapy
- subarachnoid hemorrhage
- blood brain barrier