Circadian rest-activity rhythm and longitudinal brain changes underlying late-life cognitive decline.

So Yeon JeonMin Soo ByunDahyun YiGijung JungJun-Young LeeYu Kyeong KimChul-Ho SohnKoung Mi KangYu Jin Lee Dong Young Leenull null

Published in: Psychiatry and clinical neurosciences (2022)

The findings indicate that delayed acrophase in late life may cause or predict hypometabolism at AD-signature brain regions, which underlies cognitive decline in the near future.

Keyphrases

cognitive decline
mild cognitive impairment
white matter
resting state
cerebral ischemia
current status
cross sectional
multiple sclerosis
blood brain barrier