French maritime pine bark extract (pycnogenol) in association with triple combination cream for the treatment of facial melasma in women: a double-blind, randomized, placebo-controlled trial.

Paula Basso Lima Joana Alexandria Ferreira Dias Ana Cláudia Cavalcante Esposito Luciane Donida Bartoli Miot Hélio Amarante Miot

Published in: Journal of the European Academy of Dermatology and Venereology : JEADV (2020)

Pycnogenol is well-tolerated and increases the effectiveness of broad-spectrum sunscreen and the triple combination in the treatment of facial melasma in women.

Keyphrases

double blind
polycystic ovary syndrome
randomized controlled trial
systematic review
oxidative stress
clinical trial
open label
pregnancy outcomes
metabolic syndrome
combination therapy
study protocol
pregnant women
placebo controlled
soft tissue
cervical cancer screening