Effectiveness of high-flow nasal cannula therapy on clinical outcomes in adults with COVID-19: A systematic review.
Daiana Gonçalves ArrudaGeorge Alvício KielingLucélia Luna Melo-DiazPublished in: Canadian journal of respiratory therapy : CJRT = Revue canadienne de la therapie respiratoire : RCTR (2023)
In adult patients hospitalized with COVID-19, HFNC may prove effective in reducing the rate of orotracheal intubation. The ratio of the oxygen saturation index was the parameter most examined as a predictor of HFNC success. Low-level research designs, inherent study weaknesses and inconsistent findings made it impossible to conclude whether HFNC reduces ICU length of stay or mortality. Future studies should employ higher level research designs.
Keyphrases
- coronavirus disease
- sars cov
- randomized controlled trial
- intensive care unit
- systematic review
- cardiac arrest
- cardiovascular events
- respiratory syndrome coronavirus
- risk factors
- mechanical ventilation
- finite element analysis
- respiratory failure
- case control
- cardiovascular disease
- bone marrow
- cell therapy
- acute respiratory distress syndrome
- chronic rhinosinusitis