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Refusing to TAP out: 16 new human TEIPPs identified.

Mathieu GigouxJedd D Wolchok
Published in: The Journal of experimental medicine (2018)
In this issue of JEM, Marijt et al. (https://doi.org/10.1084/jem.20180577) report their discovery of 16 novel human TAP-independent TEIPP peptides, whereas only one had been previously identified. This opens the door to new therapeutic options for patients with TAP-deficient tumors.
Keyphrases
  • endothelial cells
  • induced pluripotent stem cells
  • pluripotent stem cells
  • small molecule
  • high throughput