Eosinophils protect pressure overload- and β-adrenoreceptor agonist-induced cardiac hypertrophy.
Chongzhe YangJie LiZhiyong DengSongyuan LuoJing LiuWenqian FangFeng LiuTianxiao LiuXian ZhangYuanyuan ZhangZhaojie MengShuya ZhangJianfang LuoConglin LiuDafeng YangLijun LiuGalina K SukhovaAnastasiia SadybekovVsevolod KatritchPeter LibbyJing WangJunli GuoGuo Ping ShiPublished in: Cardiovascular research (2022)
Although blood EOS counts correlated positively with LV mass or LV mass index in humans, this study established a cardioprotective role for EOS IL4 and cationic proteins in cardiac hypertrophy and tested a therapeutic possibility of EOS cationic proteins in this human CVD.