Identification of HEPACAM2 as a novel and specific marker of small cell carcinoma.

Karen S McCollAbhishek AjayHan WangGary M WildeySuzy YoonBrandon GrubbShelby R KoppPeronne L JosephMichela SavianaGiulia RomanoPatrick Nana-SinkamCraig D PeacockZixi YunWadad MneimnehMinh LamMasaru MiyagiHung-Ying KaoAfshin Dowlati

Published in: Cancer (2024)

With its remarkable specificity, high expression, presence in early disease, and extracellular secretion, HEPACAM2 could be a potential diagnostic cell surface biomarker for early SCLC detection. These findings warrant further investigation into its role in the pathobiology of SCLC.

Keyphrases

cell surface
poor prognosis
binding protein
risk assessment
loop mediated isothermal amplification
real time pcr
climate change
bioinformatics analysis