Identification of HEPACAM2 as a novel and specific marker of small cell carcinoma.
Karen S McCollAbhishek AjayHan WangGary M WildeySuzy YoonBrandon GrubbShelby R KoppPeronne L JosephMichela SavianaGiulia RomanoPatrick Nana-SinkamCraig D PeacockZixi YunWadad MneimnehMinh LamMasaru MiyagiHung-Ying KaoAfshin DowlatiPublished in: Cancer (2024)
With its remarkable specificity, high expression, presence in early disease, and extracellular secretion, HEPACAM2 could be a potential diagnostic cell surface biomarker for early SCLC detection. These findings warrant further investigation into its role in the pathobiology of SCLC.