Comparative efficacy of exercise, diet and/or pharmacological interventions on BMI, ovulation, and hormonal profile in reproductive-aged women with overweight or obesity: a systematic review and network meta-analysis.
David Ruiz-GonzálezIván Cavero-RedondoAlba Hernández-MartínezAndrés Baena-RayaSonia Martínez-ForteSigne AltmäeAna M Fernández-AlonsoAlberto Soriano-MaldonadoPublished in: Human reproduction update (2024)
Overall, the findings of this network meta-analysis indicate that the combination of exercise, diet, and pharmacological interventions is effective for weight loss, improving ovulation, and normalizing the androgen levels of women with overweight or obesity. Although higher quality studies are needed, these results support that the optimal treatment strategy for women with overweight or obesity wishing to conceive must consider exercise, diet, and pharmacological interventions during the shared decision-making process.
Keyphrases
- weight loss
- physical activity
- bariatric surgery
- roux en y gastric bypass
- weight gain
- high intensity
- gastric bypass
- polycystic ovary syndrome
- systematic review
- resistance training
- glycemic control
- insulin resistance
- metabolic syndrome
- case control
- type diabetes
- obese patients
- randomized controlled trial
- adipose tissue
- replacement therapy