Safety Profile of Infinity Deep Brain Stimulation Electrode Placement in a 1.5T Interventional MRI Suite: Consecutive Single-Institution Case Series.
Nicholas GravbrotManojkumar SaranathanLidia Mayumi NagaeJennifer BeckerWillard S KasoffPublished in: AJNR. American journal of neuroradiology (2020)
"Asleep" deep brain stimulation using general anesthesia and intraoperative MR imaging guidance is considered "off-label" use by current FDA guidelines but is widely used in neurosurgical practice, and excellent safety has been demonstrated using first-generation, omnidirectional electrodes. Safety data for second-generation, directional electrodes in the interventional MR imaging environment have not yet been published. Herein, we report 34 cases of asleep deep brain stimulation using second-generation, directional electrodes in an interventional MR imaging suite at a single institution. Procedural complications and imaging data are described. All patients underwent postoperative MR imaging with fully implanted ("internalized") electrodes after scalp closure; 4 patients also underwent MR imaging with "externalized" electrodes before scalp closure. No MR imaging-related complications were observed, and procedural complication rates were comparable to prior series. This suggests that the use of second-generation, directional electrodes in the interventional MR imaging environment appears to be safe when following manufacturer-published imaging guidelines.
Keyphrases
- deep brain stimulation
- contrast enhanced
- parkinson disease
- obsessive compulsive disorder
- end stage renal disease
- magnetic resonance imaging
- reduced graphene oxide
- chronic kidney disease
- carbon nanotubes
- high resolution
- newly diagnosed
- ejection fraction
- computed tomography
- patients undergoing
- prognostic factors
- solid state
- healthcare
- magnetic resonance
- primary care
- electronic health record
- randomized controlled trial
- gold nanoparticles
- mass spectrometry
- artificial intelligence
- meta analyses