Candidate genes involved in the defunctionalization and refunctionalization of the urinary bladder induced by bladder anuria and reperfusion.
Yusuke KisouTakamitsu InoueKazutoshi NishijimaMinguo HuangRyohei YamamotoAtsushi KoizumiTaketoshi NaraKazuyuki NumakuraMitsuru SaitoShintaro NaritaShigeru SatohTomonori HabuchiPublished in: Neurourology and urodynamics (2020)
The present study using novel model of bladder defunctionalization followed by refunctionalization indicated the consistent downregulation of UPK1B and CST6 in muscle and the consistent downregulation of IGFBP2 in mucosa in process of bladder defunctionalization, which was validated by human specimens.