Expression of Inflammatory Genes in Murine Lungs in a Model of Experimental Pulmonary Hypertension: Effects of an Antibody-Based Targeted Delivery of Interleukin-9.
Judith HeissKatja GrünIsabell SingererLaura TempelMattia MatasciChristian JungAlexander PfeilPaul Christian SchulzeDario NeriMarcus FranzPublished in: Advances in respiratory medicine (2024)
In accordance with the hypothesis stated above, F8IL9 treatment diminished the upregulation of some genes associated with inflammation in a PH animal model. Therefore, we hypothesize that IL9-based immunocytokine treatment will likely modulate various inflammatory pathways.