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The effect of BACE1-AS on β-amyloid generation by regulating BACE1 mRNA expression.

Fan LiYun WangHui YangYingying XuXiaoyan ZhouXiao ZhangZhaohong XieJianzhong Bi
Published in: BMC molecular biology (2019)
The mechanism by which exogenous Aβ1-42 induces BACE1 expression and Aβ generation is mediated by BACE1-AS. BACE1-AS is involved in the mechanism regulating BACE1 expression and Aβ generation in APPsw transgenic cells.
Keyphrases
  • poor prognosis
  • induced apoptosis
  • binding protein
  • cell cycle arrest
  • signaling pathway
  • long non coding rna
  • cell death
  • pi k akt