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Enhanced production of interleukin-29 and related genes are associated with T helper 1 cell parameters in patients with type 2 diabetes mellitus.
Zahra Sardarmelli
Vida Sheikh
Ghasem Solgi
Mahdi Behzad
Published in:
Human immunology (2023)
Abnormal expression levels of IL-29- and Th1- related genes are linked with T2DM pathogenesis. IL-29 may amplify the expression of Th1-specific genes especially TNF-α by upregulating NFATc1 expression.
Keyphrases
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poor prognosis
binding protein
rheumatoid arthritis
long non coding rna
stem cells
immune response
cell therapy
metabolic syndrome
adipose tissue
mesenchymal stem cells
dna methylation
skeletal muscle
insulin resistance
weight loss