Nanoconjugates-Based Stem Cell Therapy for the Management of COVID-19.
Drashti DesaiPravin K ShendePublished in: Stem cell reviews and reports (2020)
A potential ability of stem cells (SCs) is to regenerate and repair tissues in the human body by providing great prospects for therapeutic applications in the field of medicine. Currently, SC therapy is used in various conditions like diabetes, neurodegenerative disorders, etc. but faces some limitations like patient biocompatibility and chances of cross-infection. SCs are further modulated with nanoconjugates to overcome such challenges and will offer an advantage in the treatment of COVID-19. This pandemic requires design and development of proper treatment to save the life of human beings. Advancements in SC-based nanoconjugated therapy will open new avenues and create a significant impact in the development of futuristic nanomedicine. It may also emerge as a potential therapy for the management of infection in patients suffering from SARS-CoV-2 and related diseases such as pneumonia and virus-induced lung injuries. Graphical abstract Mechanisms of stem cell-based nanoconjugates for inhibition of replication of corona virus.
Keyphrases
- stem cells
- sars cov
- coronavirus disease
- endothelial cells
- respiratory syndrome coronavirus
- cell therapy
- type diabetes
- cardiovascular disease
- high glucose
- induced pluripotent stem cells
- newly diagnosed
- ejection fraction
- gene expression
- cancer therapy
- human health
- risk assessment
- pluripotent stem cells
- mesenchymal stem cells
- climate change
- oxidative stress
- case report
- chronic kidney disease
- skeletal muscle
- bone marrow
- glycemic control