Breast cancer stem cells characterized by CD70 expression preferentially metastasize to the lungs.

Li LiuBo YinZhu YiXiuJuan LiuZhiQian HuWenChao GaoHaiWen YuQingQuan Li

Published in: Breast cancer (Tokyo, Japan) (2018)

We isolated CSCs from primary human breast cancers and found that CD70 + subpopulations mediate lung-specific metastasis. These findings might be used to aid in selection of patients for postoperative adjuvant therapy.

Keyphrases

stem cells
end stage renal disease
endothelial cells
ejection fraction
newly diagnosed
poor prognosis
patients undergoing
peritoneal dialysis
patient reported outcomes
nk cells
cell therapy
young adults
cancer stem cells