Evaluation of the effect of eltrombopag therapy on the platelet collagen receptor glycoprotein VI (GPVI) expression and soluble GPVI levels in young patients with immune thrombocytopenia.

Azza Abdel Gawad TantawyNayera Hazaa Khalil ElsherifFatma Soliman EbeidRasha Abd El-Rahman El-GamalEman Abdel Rahman IsmailMahmoud A KennyMichael Botros Elkes Morcos

Published in: Journal of thrombosis and thrombolysis (2022)

Our data suggest that eltrombopag, through its effect on the GPVI receptor expression and its soluble form, might reduce bleeding manifestations and improve the quality of life of chronic and persistent ITP children independent of its effect on the platelet count.

Keyphrases

poor prognosis
young adults
binding protein
electronic health record
atrial fibrillation
big data
middle aged
stem cells
wound healing
machine learning
long non coding rna
bone marrow
smoking cessation
replacement therapy