Metabolomic Fingerprints of Medical Therapy Versus Bariatric Surgery in Patients With Obesity and Type 2 Diabetes: The STAMPEDE Trial.
Christopher L AxelrodAdithya HariWagner S DantasSangeeta R KashyapPhilip R SchauerJohn P KirwanPublished in: Diabetes care (2024)
We identified a novel metabolomic fingerprint characterizing the longer-term adaptations to MT, RYGB, and SG. Notably, the metabolomic profiles of RYGB and SG procedures were distinct, indicating equivalent weight loss may be achieved by divergent effects on metabolism.
Keyphrases
- weight loss
- roux en y gastric bypass
- bariatric surgery
- type diabetes
- gastric bypass
- glycemic control
- obese patients
- healthcare
- insulin resistance
- clinical trial
- study protocol
- preterm infants
- metabolic syndrome
- high intensity
- randomized controlled trial
- adipose tissue
- high fat diet induced
- quality control
- smoking cessation
- replacement therapy