Impact of Natural Killer (NK) Cells on Immune Reconstitution, and Their Potential as a Biomarker of Disease Activity, in Alemtuzumab-Treated Patients with Relapsing Remitting Multiple Sclerosis: An Observational Study.
Serena PalmeriMarta PonzanoFederico IvaldiAlessio SignoriCaterina LapucciValentina CasellaMaria Teresa FerròTiziana VigoMatilde IngleseGiovanni Luigi MancardiAntonio UccelliAlice LaroniPublished in: CNS drugs (2021)
The results of this study provide novel evidence that NK cells influence reconstitution of adaptive immune cells upon alemtuzumab and that patients with a successful response to alemtuzumab have an early immune reconstitution dominated by NK cells.