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Long noncoding RNA SNHG16 regulates TLR4-mediated autophagy and NETosis formation in alveolar hemorrhage associated with systemic lupus erythematosus.

Yu-Tung HsiehYi-Cheng ChenYu-Chi ChouPin-Yu KuoYi-Ting YenHung-Wen TsaiChrong-Reen Wang
Published in: Journal of biomedical science (2023)
Our results demonstrate that lncRNA SNHG16 regulates TLR4-mediated autophagy and NETosis formation in the human and mouse AH lungs, and provide a therapeutic potential of intra-pulmonary delivery of shRNA targeting SNHG16 in this SLE-related lethal manifestation.
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