Impact of chest wall deformity on cardiac function by CMR and feature-tracking strain analysis in paediatric patients with Marfan syndrome.

Hy Van LamMichael GrothThomas MirPeter BannasGunnar K LundCharlotte M JahnkeMalte WarnckeKai-Jonathan MaasGerhard AdamJochen HerrmannEnver Tahir

Published in: European radiology (2020)

• Paediatric Marfan patients demonstrate reduced RV volume and ejection fraction compared to healthy controls. • A concordant attenuation in RV global longitudinal strain was observed in Marfan patients, while the RV global circumferential strain was increased, indicating a possible compensatory mechanism. • Subgroup analyses demonstrated alterations in RV ejection fraction and RV/LV global strain parameters, indicating a possible association of severe chest wall deformity with biventricular dysfunction in paediatric Marfan patients.

Keyphrases

ejection fraction
aortic stenosis
mycobacterium tuberculosis
end stage renal disease
chronic kidney disease
newly diagnosed
intensive care unit
clinical trial
prognostic factors
heart failure
randomized controlled trial
patient reported outcomes
deep learning
patient reported
aortic valve