Unravelling relationships between obesity, diabetes, and factors related to somatosensory functioning in knee osteoarthritis patients.
Lotte MeertSophie VervullensChristiaan H W HeusdensRob J E M SmeetsMira MeeusMichel G C A M MertensPublished in: Clinical rheumatology (2024)
The findings indicate that fat mass may be closely associated with altered somatosensory functioning in patients with knee OA. However, no significant correlations were found between BMI or HbA1c levels and pain-related outcomes. Future research should focus on longitudinal studies to elucidate the causal relationships and further explore the impact of metabolic factors on pain mechanisms in this patient population. Key Points • The findings indicate that fat mass may be closely associated with altered somatosensory functioning in patients with knee OA.
Keyphrases
- knee osteoarthritis
- chronic pain
- type diabetes
- end stage renal disease
- adipose tissue
- pain management
- transcranial direct current stimulation
- neuropathic pain
- newly diagnosed
- ejection fraction
- metabolic syndrome
- total knee arthroplasty
- chronic kidney disease
- insulin resistance
- body mass index
- cardiovascular disease
- weight gain
- weight loss
- prognostic factors
- peritoneal dialysis
- spinal cord
- patient reported outcomes
- physical activity
- cross sectional
- working memory
- drug induced
- postoperative pain
- patient reported