Maintenance of Enteral ACE2 Prevents Diabetic Retinopathy in Type 1 Diabetes.

Ram PrasadJason L FloydMariana D DupontAngela HarbourYvonne Adu AggyeiwaahBright Asare-BediakoDibyendu ChakrabortyKara KichlerAayush RohellaSergio Li CalziRegina LammendellaJustin WrightMichael E Boulton Gavin Y Oudit Mohan K RaizadaBruce R StevensQiuhong LiMaria B Grant

Published in: Circulation research (2022)

mice, maintaining intestinal ACE2 expression prevented and reversed DR, emphasizing the multifaceted role of the intestinal renin-angiotensin system in diabetes and DR.

Keyphrases

diabetic retinopathy
type diabetes
glycemic control
angiotensin converting enzyme
editorial comment
optical coherence tomography
angiotensin ii
cardiovascular disease
poor prognosis
insulin resistance
high fat diet induced
binding protein
long non coding rna
skeletal muscle
adipose tissue
wild type