Nrf2 protects against seawater drowning-induced acute lung injury via inhibiting ferroptosis.

Yu-Bao QiuBin-Bin WanGang LiuYa-Xian WuDan ChenMu-Dan LuJun-Liang ChenRen-Qiang YuDao-Zhen ChenQing-Feng Pang

Published in: Respiratory research (2020)

These results suggested that Nrf2 can inhibit ferroptosis and therefore alleviate ALI induced by seawater drowning. The effectiveness of ferroptosis inhibition by Nrf2 provides a novel therapeutic target for seawater drowning-induced ALI.

Keyphrases

cell death
oxidative stress
diabetic rats
high glucose
molecularly imprinted
randomized controlled trial
systematic review
drug induced
lipopolysaccharide induced
signaling pathway
lps induced
mass spectrometry
tandem mass spectrometry