Large Skull Metastasis in Follicular Thyroid Carcinoma: A Comprehensive Case Presentation and Systematic Review.

Gianluca ScaliaMassimiliano PorzioRoberta CostanzoEliana GiuratoFabio GibiliscoDomenico Gerardo IacopinoRosario MaugeriGiovanni Federico NicolettiGiuseppe Emmanuele Emmanuele UmanaRaffaele Alessandrello

Published in: Journal of neurological surgery. Part A, Central European neurosurgery (2024)

Managing secondary skull metastases from FTC requires a comprehensive approach, including surgical intervention, radiotherapy, and potential systemic therapies. The rarity of these metastases underscores the need for further research to establish standardized treatment guidelines, explore molecular profiling, and investigate immunotherapy and combination therapies, offering hope for improved outcomes in this challenging clinical scenario.

Keyphrases

systematic review
randomized controlled trial
meta analyses
early stage
radiation therapy
single cell
radiation induced
locally advanced
squamous cell carcinoma
metabolic syndrome
adipose tissue
climate change
skeletal muscle
insulin resistance