Incidence of serum antibodies to xenoantigens on triple-knockout pig cells in different human groups.

Songzhe He Tao LiHao FengJiaxiang DuDavid K C Cooper Hidetaka HaraHongtao JiangDengke Pan Gang ChenYi Wang

Published in: Xenotransplantation (2023)

Human sera contain IgM antibodies against unknown pig xenoantigens expressed on TKO/hCD55 pPBMCs. Although not confirmed in the present study, the targets for these antibodies may include swine leukocyte antigens.

Keyphrases

endothelial cells
induced pluripotent stem cells
induced apoptosis
pluripotent stem cells
oxidative stress
signaling pathway
cell proliferation