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The numbers of peripheral regulatory T cells are reduced in patients with psoriatic arthritis and are restored by low-dose interleukin-2.

Jia WangSheng-Xiao ZhangYu-Fei HaoMeng-Ting QiuJing LuoYu-Yao LiChong GaoXiao-Feng Li
Published in: Therapeutic advances in chronic disease (2020)
PsA patients exhibited low Treg numbers. Low-dose IL-2 combination treatment increased these numbers and relieved disease activity without any apparent side effects. Additional studies are required to explore the long-term immunoregulatory utility of IL-2 treatment.
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