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The Meaning and Reliability of Minimal Important Differences (MIDs) for Clinician-Reported Outcome Measures (ClinROMs) in Dermatology-A Scoping Review.

Speeckaert ReinhartArno BelpaireSandrine HerbeletMarijn M SpeeckaertNanja van Geel
Published in: Journal of personalized medicine (2022)
MIDs of ClinROMs for skin disorders should be carefully interpreted due to the substantial differences in methodology between the studies. There is an urgent need for a consensus method to report reliable MIDs. Otherwise, this lack of uniformity could not only affect the design and conclusion of clinical trials but also skew treatment decisions.
Keyphrases
  • clinical trial
  • randomized controlled trial
  • clinical practice
  • wound healing
  • phase ii
  • palliative care
  • open label
  • phase iii
  • double blind
  • placebo controlled