A phase II, single-center, double-blind, randomized placebo-controlled trial to explore the efficacy and safety of intravenous melatonin in patients with COVID-19 admitted to the intensive care unit (MelCOVID study): a structured summary of a study protocol for a randomized controlled trial.

Miguel Rodríguez-RubioJuan Carlos FigueiraDarío Acuña-CastroviejoAlberto M BorobiaGermaine EscamesPedro De la Oliva

Published in: Trials (2020)

EU Clinical Trials Register. Date of trial registration: 10 July 2020. URL: https://www.clinicaltrialsregister.eu/ctr-search/trial/2020-001808-42/ES FULL PROTOCOL: The full protocol is attached as an additional file, accessible from the Trials website (Additional file 1). In the interest of expediting dissemination of this material, the familiar formatting has been eliminated; this Letter serves as a summary of the key elements of the full protocol.

Keyphrases

phase ii
double blind
clinical trial
placebo controlled
phase iii
open label
randomized controlled trial
study protocol