Overexpression of FHL1 suppresses papillary thyroid cancer proliferation and progression via inhibiting Wnt/β-catenin pathway.

Junxin ChenChuimian ZengJiewen JinPengyuan ZhangYilin ZhangHanrong ZhangYanbing LiHongyu Guan

Published in: Endocrine (2024)

FHL1 is downregulated in PTC and its expression is associated with better clinical outcomes for patients with the disease. FHL1 acts as a tumor suppressor via, at least partially, suppressing Wnt/β-catenin pathway.

Keyphrases

signaling pathway
cell proliferation
stem cells
poor prognosis
transcription factor
binding protein