Decision-making and autonomy among participants in early-phase cancer immunotherapy trials: a qualitative study.
Jonathan AveryJennifer A H BellKhotira BaryolayGary RodinRinat NissimLynda G BalneavesPublished in: BMC cancer (2024)
Findings highlight the continuum of perceived choice that exists among patients with cancer when considering participation in early-phase cancer immunotherapy CTs. All participants were interpreted as exhibiting some degree of relational autonomy within the psychosocial and structural context of early-phase CT decision making. This study offers insights into the intersection of cancer care delivery, personal beliefs and values, and established CT processes and structures that can inform future practices and policies associated with early-phase cancer immunotherapy CTs to better support patients in making informed decisions.