Effect of serum concentration and concomitant drugs on vancomycin-induced acute kidney injury in haematologic patients: a single-centre retrospective study.

Naoto OkadaMasayuki ChumaMomoyo AzumaShingen NakamuraHirokazu MikiHirofumi HamanoMitsuhiro GodaKenshi TakechiYoshito ZamamiMasahiro AbeKeisuke Ishizawa

Published in: European journal of clinical pharmacology (2019)

The optimal initial VCM trough concentration was 10-15 mg/L in haematologic patients, considering safety and effectiveness. There were differences in the effect of VCM-induced AKI between nephrotoxic drugs.

Keyphrases

end stage renal disease
newly diagnosed
ejection fraction
chronic kidney disease
randomized controlled trial
peritoneal dialysis
diabetic rats
patient reported outcomes
staphylococcus aureus