NFE2L2/NRF2, OGG1, and cytokine responses of human gingival keratinocytes against oxidative insults of various origin.

Gökhan KasnakEija KönönenStina SyrjänenMervi GürsoyFares Zeidán-ChuliáErhan FiratliUlvi K Gürsoy

Published in: Molecular and cellular biochemistry (2018)

Pg LPS, nicotine, and 4-NQO induce oxidative stress and regulate anti-oxidative response and cytokine expressions in human gingival keratinocytes differently. These results may indicate that bacterial and tobacco-related insults regulate distinct pathways.

Keyphrases

oxidative stress
endothelial cells
induced pluripotent stem cells
pluripotent stem cells
inflammatory response
smoking cessation
anti inflammatory
induced apoptosis
heat shock